has material basis in germline mutation in disease has feature SALL4 Strabismus autosomal dominant disease syndromic disease Duane-radial ray syndrome https://github.com/monarch-initiative/mondo/issues/4948 https://github.com/monarch-initiative/mondo/issues/6878 https://rarediseases.info.nih.gov/diseases/9182/duane-radial-ray-syndrome https://www.malacards.org/card/duane_radial_ray_syndrome Duane anomaly with radial ray abnormalities and deafness DOID:0060747 Duane-radial ray syndrome A syndrome of multiple congenital anomalies and is characterized by ocular manifestations (uni- or bilateral Duane anomaly (95% of cases), congenital optic nerve hypoplasia or optic disk coloboma), bilateral deafness and radial ray malformation that can include thenar hypoplasia and/or hypoplasia or aplasia of the thumbs; hypoplasia or aplasia of the radii; shortening and radial deviation of the forearms; triphalangeal thumbs; and duplication of the thumb (preaxial polydactyly).The phenotype overlaps with other SALL4>/i> related disorders including acro-renal-ocular syndrome and Holt-Oram syndrome (see these terms). Transmission is autosomal dominant. OMIM:607323 Duane anomaly with radial abnormalities and deafness GARD:0009182 DR syndrome Orphanet:959 Okihiro syndrome MONDO:0011812 ICD9:759.89 UMLS:C1623209 Orphanet:93293 DRRS MEDGEN:301647 SCTID:699867001 acro-renal-ocular syndrome SCTID:720415006 obsolete neuro-ophthalmological disease dysostosis congenital limb malformation non-syndromic limb reduction defect