has material basis in germline mutation in FSHR hereditary disease ovarian disorder ovarian hyperstimulation syndrome https://www.malacards.org/card/ovarian_hyperstimulation_syndrome SCTID:129635004 MESH:D016471 ovarian hyperstimulation syndrome OHSS Orphanet:64739 ovarian hyperstimulation syndrome, familial gestational spontaneous OMIM:608115 A complication of ovulation induction in infertility treatment. It is graded by the severity of symptoms which include ovary enlargement, multiple ovarian follicles; ovarian cysts; ascites; and generalized edema. The full-blown syndrome may lead to renal failure, respiratory distress, and even death. Increased capillary permeability is caused by the vasoactive substances, such as vascular endothelial growth factors, secreted by the overly-stimulated ovaries. UMLS:C0085083 DOID:5425 MONDO:0011972 GARD:0016668 MedDRA:10033266 icd11.foundation:1216664013 MEDGEN:38966 ICD9:256.1