has material basis in germline mutation in NOTCH3 familial partial lipodystrophy, Kobberling type https://www.malacards.org/card/lipodystrophy_familial_partial_type_1 familial partial lipodystrophy type 1 DOID:0070207 Familial partial lipodystrophy, Kobberling type, is a very rare form of familial partial lipodystrophy (FPLD) of unknown etiology characterized by lipoatrophy that is confined to the limbs and a normal or increased fat distribution of the face, neck, and trunk. Arterial hypertension and diabetes have also been associated. Inheritance is thought to be autosomal dominant. FPLD1 SCTID:725035001 familial partial lipodystrophy type Köbberling Orphanet:79084 GARD:0012598 MONDO:0012072 MEDGEN:318591 UMLS:C1720859 OMIM:608600 lipodystrophy, familial partial, Kobberling type familial partial lipodystrophy, Köbberling type lipodystrophy, familial partial, type 1 familial partial lipodystrophy