has material basis in germline mutation in MYH8 Carney complex - trismus - pseudocamptodactyly syndrome https://www.malacards.org/card/carney_complex_variant Orphanet:319340 OMIM:608837 MEDGEN:332400 Carney complex variant UMLS:C1837245 GARD:0017448 MONDO:0012137 Carney complex-trismus-pseudocamptodactyly syndrome is a rare genetic heart-hand syndrome characterized by typical manifestations of the Carney complex (spotty pigmentation of the skin, familial cardiac and cutaneous myxomas and endocrinopathy) associated with trismus and distal arthrogryposis (presenting as involuntary contraction of distal and proximal interphalangeal joints of hands evident only on dorsiflexion of wrist and similar lower-limb contractures producing foot deformities). Carney complex heart-hand syndrome