has material basis in germline mutation in FREM1 bifid nose syndromic disease BNAR syndrome https://github.com/monarch-initiative/mondo/issues/6878 https://www.malacards.org/card/bifid_nose_with_or_without_anorectal_and_renal_anomalies bifid nose with or without anorectal and renal anomalies MESH:C567672 MEDGEN:413305 BNAR syndrome is a very rare multiple congenital anomaly syndrome characterized by a bifid nose (with bulbous nasal tip but not associated with hypertelorism) with or without the presence of anal defects (i.e. anteriorly placed anus, rectal stenosis or atresia) and renal dysplasia (unilateral or bilateral renal agenesis) and without intellectual disability. BNAR syndrome is phenotypically related to Fraser syndrome and oculotrichoanal syndrome. BNAR UMLS:C2750433 Orphanet:217266 OMIM:608980 bifid NOSE with or without anorectal and renal anomalies SCTID:717940006 MONDO:0012165 GARD:0010595 multiple congenital anomalies/dysmorphic syndrome without intellectual disability hereditary otorhinolaryngologic disease