has material basis in germline mutation in KCNMA1 generalized epilepsy-paroxysmal dyskinesia syndrome https://www.malacards.org/card/paroxysmal_nonkinesigenic_dyskinesia_3 https://www.malacards.org/card/paroxysmal_nonkinesigenic_dyskinesia_3_with_or_without_generalized_epilepsy_2 generalized epilepsy and paroxysmal dyskinesia GARD:0016704 DOID:0070442 Orphanet:79137 UMLS:C5574945 MESH:C563719 PNKD3 paroxysmal nonkinesigenic dyskinesia, 3, with or without generalised epilepsy generalised epilepsy and paroxysmal dyskinesia MEDGEN:1801137 Generalized epilepsy-paroxysmal dyskinesia syndrome is characterized by the association of paroxysmal dyskinesia and generalized epilepsy (usually absence or generalized tonic-clonic seizures) in the same individual or family. The prevalence is unknown. Analysis in one of the reported families led to the identification of a causative mutation in the KCNMA1 gene (chromosome 10q22), encoding the alpha subunit of the BK channel. Transmission is autosomal dominant. GEPD MONDO:0012276 OMIM:609446 familial partial epilepsy