has material basis in germline mutation in ZIC2 holoprosencephaly 5 https://github.com/monarch-initiative/mondo/issues/7693 https://www.malacards.org/card/holoprosencephaly_5_2 UMLS:C1864827 DOID:0110878 OMIM:609637 NCIT:C75460 MONDO:0012322 GARD:0024860 HPE5 MESH:C566464 holoprosencephaly 5 MEDGEN:355304 holoprosencephaly caused by mutation in ZIC2 holoprosencephaly type 5 ZIC2 holoprosencephaly Holoprosencephaly associated with mutations in the ZIC2 gene. holoprosencephaly microform holoprosencephaly lobar holoprosencephaly alobar holoprosencephaly