has material basis in germline mutation in POMC obesity due to pro-opiomelanocortin deficiency https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/obesity_due_to_pro_opiomelanocortin_deficiency https://www.malacards.org/card/obesity_early_onset_with_adrenal_insufficiency_and_red_hair Pro-opiomelanocortin (POMC) deficiency is a form of monogenic obesity resulting in severe early-onset obesity, adrenal insufficiency, red hair and pale skin. UMLS:C1857854 obesity, early-onset, with adrenal insufficiency and Red hair obesity, adrenal insufficiency, and red hair due to POMC deficiency ICD9:255.5 MEDGEN:341863 POMC Deficiency MONDO:0012335 PROOPIOMELANOCORTIN deficiency GARD:0010823 icd11.foundation:530374033 POMC deficiency OBAIRH obesity, early-onset, with adrenal insufficiency and RED hair OMIM:609734 MESH:C565726 Orphanet:71526 SCTID:702949005 NORD:110450 obesity, early-onset, adrenal insufficiency, and Red hair inherited obesity