has material basis in germline mutation in AFG3L2 spinocerebellar ataxia type 28 https://www.malacards.org/card/spinocerebellar_ataxia_28 MEDGEN:339941 Orphanet:101109 Spinocerebellar ataxia type 28 (SCA28) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I). It is characterized by juvenile onset, slowly progressive cerebellar ataxia due to Purkinje cell degeneration. icd11.foundation:2020736035 MONDO:0012450 spinocerebellar ataxia type 28 DOID:0050977 UMLS:C1853249 spinocerebellar ataxia 28 GARD:0009951 MESH:C537205 SCTID:715824008 OMIM:610246 SCA28 mitochondrial oxidative phosphorylation disorder autosomal dominant cerebellar ataxia type I