disease has primary infectious agent herpes simplex infectious disease viral encephalitis herpes simplex encephalitis https://rarediseases.info.nih.gov/diseases/6649/herpes-simplex-encephalitis https://www.malacards.org/card/herpes_simplex_virus_encephalitis Simplexvirus caused infectious encephalitis HSV encephalitis MESH:D020803 icd11.foundation:320069644 MEDGEN:75794 NANDO:2200772 HSVE HSE Orphanet:1930 Herpes simplex virus encephalitis (HSE) is caused by the infection of the central nervous system by Herpes simplex virus (HSV) that could have a devastating clinical course and a potentially fatal outcome particularly with delay or lack of treatment. HSV often involves the frontal and temporal lobes, usually asymmetrically, resulting in personality changes, cognitive impairment, aphasia, seizures, and focal weakness. MONDO:0012521 NORD:1087 NCIT:C84762 Simplexvirus infectious encephalitis Herpes simplex neuroinvasion Encephalitis, Herpes Simplex UMLS:C0276226 herpetic encephalitis GARD:0006649 Herpes simplex meningo-encephalitis obsolete infectious disease with epilepsy obsolete hereditary predisposition to infections infectious encephalitis obsolete infectious disease with dementia Simplexvirus