has material basis in germline mutation in SYNE1 autosomal recessive ataxia, Beauce type https://www.malacards.org/card/spinocerebellar_ataxia_autosomal_recessive_8 recessive ataxia of Beauce autosomal recessive cerebellar ataxia type 1 OMIM:610743 MEDGEN:343973 spinocerebellar ataxia, autosomal recessive type 8 MONDO:0012549 autosomal recessive ataxia Beauce type GARD:0012234 spinocerebellar ataxia, autosomal recessive 8 A rare disorder characterized by a slowly progressive pure cerebellar ataxia associated with dysarthria. It has been described in 53 individuals from 26 families of Canadian origin. The mode of transmission is autosomal recessive. Positional cloning has led to the identification of several gene mutations. ARCA1 autosomal recessive spinocerebellar ataxia 8 SYNE1-related autosomal recessive cerebellar ataxia Orphanet:88644 spinocerebellar ataxia autosomal recessive 8 DOID:0111618 UMLS:C1853116 SCAR8 autosomal recessive cerebellar ataxia