has material basis in germline mutation in IRX5 hereditary disease craniofacial dysplasia - osteopenia syndrome https://www.malacards.org/card/hamamy_syndrome MONDO:0012634 HAMAMY syndrome GARD:0017422 MESH:C566988 OMIM:611174 Orphanet:314555 UMLS:C1970027 Hamamy syndrome MEDGEN:370148 hypertelorism, Severe, with midface prominence, myopia, mental retardation, and bone fragility HMMS disorder of development or morphogenesis