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        <rdfs:label>has material basis in germline mutation in</rdfs:label>
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    <!-- http://identifiers.org/hgnc/20249 -->

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        <rdfs:label>SPRED1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0012669 -->

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        <rdfs:label>Legius syndrome</rdfs:label>
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        <ns5:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/legius_syndrome</ns5:curated_content_resource>
        <oboInOwl:hasExactSynonym>NF1-like syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>neurofibromatosis 1-like syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C1969623</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Legius syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:611431</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DOID:0070484</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>icd11.foundation:1025118245</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MEDGEN:370709</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Orphanet:137605</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C176941</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:C548032</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>neurofibromatosis type 1-like syndrome</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>neurofibromatosis type 1 like syndrome</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>GARD:0010714</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0012669</oboInOwl:id>
        <ns4:IAO_0000115>Legius syndrome, also known as NF1-like syndrome, is a rare, genetic skin pigmentation disorder characterized by multiple cafC)-au-lait macules with or without axillary or inguinal freckling.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>SCTID:703541007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:709.09</oboInOwl:hasDbXref>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0019289 -->

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        <rdfs:label>hyperpigmentation of the skin</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0019755 -->

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        <rdfs:label>developmental defect during embryogenesis</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0020297 -->

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        <rdfs:label>Noonan syndrome and Noonan-related syndrome</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0100118 -->

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        <rdfs:label>hereditary skin disorder</rdfs:label>
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