disease arises from structure disease arises from alteration in structure 10q23 (Human) syndrome caused by partial chromosomal deletion chromosome 10q23 deletion syndrome https://github.com/monarch-initiative/mondo/issues/3664 https://www.malacards.org/card/chromosome_10q223_q232_deletion_syndrome https://www.malacards.org/card/chromosome_10q23_deletion_syndrome MESH:C567385 deletion 10q22.3q23.3 MONDO:0012830 10q22.3q23.3 microdeletion syndrome is a rare partial autosomal monosomy characterized by a mild facial dysmorphism variably including macrocephaly, broad forehead, hypertelorism or hypotelorism, deep-set eyes, upslanting or downslanting palpebral fissures, low-set ears, flat nasal bridge, smooth philtrum, thin upper lip), cleft palate, cerebellar and cardiac malformations, psychomotor development delay, and behavioral abnormalities (attention deficit hyperactivity disorder, autism). Other rare features may include congenital breast aplasia, arachnodactyly, joint hyperlaxity, club feet, feeding difficulties, failure to thrive. MEDGEN:906099 Orphanet:276413 monosomy 10q22.3q23.3 Del(10)(q22.3q23.3) DOID:0060389 OMIM:612242 GARD:0017280 UMLS:C4225669 10q22.3q23 microdeletion syndrome partial monosomy of the long arm of chromosome 10