has material basis in germline mutation in disease has feature FGFR3 Strabismus autosomal dominant disease inherited focal segmental glomerulosclerosis Crouzon syndrome-acanthosis nigricans syndrome https://github.com/monarch-initiative/mondo/issues/4948 https://www.malacards.org/card/crouzon_syndrome_with_acanthosis_nigricans GARD:0016810 SCTID:702361006 Crouzon syndrome with acanthosis nigricans (CAN) is a very rare, clinically heterogeneous form of faciocraniostenosis with Crouzon-like features and premature synostosis of cranial sutures (Crouzon disease), associated with acanthosis nigricans (AN). UMLS:C2677099 NCIT:C38145 MEDGEN:394201 Crouzon syndrome with acanthosis nigricans MESH:C567382 OMIM:612247 Crouzonodermoskeletal syndrome Orphanet:93262 chronic allograft nephropathy CAN Chronic kidney allograft nephropathy MONDO:0012833 Crouzon-dermoskeletal syndrome DOID:0111161 syndromic craniosynostosis obsolete neuro-ophthalmological disease