has material basis in germline mutation in AP4M1 hereditary spastic paraplegia 50 https://github.com/monarch-initiative/mondo/issues/7693 https://www.malacards.org/card/spastic_paraplegia_50_autosomal_recessive DOID:0110802 MESH:C567858 SPG50 hereditary spastic paraplegia caused by mutation in AP4M1 hereditary spastic paraplegia type 50 GARD:0015592 UMLS:C2752008 Spastic Paraplegia 50 Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the AP4M1 gene. spastic paraplegia 50, autosomal recessive cerebral palsy, spastic quadriplegic, 3 AP4M1 hereditary spastic paraplegia OMIM:612936 MONDO:0013048 MEDGEN:442869 NORD:1989 hereditary spastic paraplegia AP-4 deficiency syndrome