has material basis in germline mutation in ITK lymphoproliferative syndrome 1 https://github.com/monarch-initiative/mondo/issues/9285 https://www.malacards.org/card/lymphoproliferative_syndrome https://www.malacards.org/card/lymphoproliferative_syndrome_1 MONDO:0013081 MEDGEN:765548 MESH:C567815 NCIT:C126344 LPFS1 A condition of decreased or absent presence or activity of IL2-inducible t-cell kinase. Deficiency of this protein is associated with lymphoproliferative syndrome 1, an autosomal recessive primary immunodeficiency characterized by onset in early childhood of Epstein-Barr virus (EBV)-associated immune dysregulation, manifest as lymphoma, lymphomatoid granulomatosis, hemophagocytic lymphohistiocytosis, Hodgkin disease, and/or hypogammaglobulinemia.. DOID:0060707 Orphanet:538963 lymphoproliferative syndrome 1 ITK lymphoproliferative syndrome OMIM:613011 lymphoproliferative syndrome caused by mutation in ITK GARD:0017979 UMLS:C3552634 ITK deficiency NANDO:2200734 lymphoproliferative syndrome type 1 obsolete autosomal recessive lymphoproliferative disease lymphoproliferative syndrome non-SCID combined immunodeficiency immunodeficiency disease