has material basis in germline mutation in CYP19A1 aromatase deficiency https://rarediseases.info.nih.gov/diseases/365/aromatase-deficiency https://www.malacards.org/card/aromatase_deficiency UMLS:C1960539 Orphanet:91 MESH:C537436 aromatase deficiency icd11.foundation:260189446 congenital estrogen deficiency NCIT:C120144 MEDGEN:743307 Aromatase deficiency disrupts the synthesis of estradiol, resulting in hirsutism of mothers during gestation of an affected child; pseudohermaphroditism and virilization in women; and tall stature, osteoporosis and obesity in men. OMIM:613546 congenital oestrogen deficiency MONDO:0013301 pseudohermaphroditism, female, due to placental aromatase deficiency GARD:0000365 inherited primary ovarian failure pregnancy disorder obsolete hereditary 46,XX disorder of sex development