disease has major feature Syndactyly ectodermal dysplasia-syndactyly syndrome https://www.malacards.org/card/ectodermal_dysplasia_syndactyly_syndrome_1 UMLS:C4749852 MONDO:0013311 EDSS ectodermal dysplasia-syndactyly syndrome type 1 Orphanet:247820 Ectodermal dysplasia-syndactyly syndrome is a rare, genetic ectodermal dysplasia syndrome characterized by sparse to absent scalp hair, eyebrows, and eyelashes (with pili torti when present), widely spaced, conical-shaped teeth with peg-shaped, conical crowns and enamel hypoplasia and palmoplantar hyperkeratosis, associated with partial cutaneous syndactyly in hands and feet. GARD:0017198 EDSS1 MEDGEN:1648397 ectodermal dysplasia-syndactyly syndrome 1 OMIMPS:613573 ectodermal dysplasia syndrome