cardiac rhythm disease torsade-de-pointes syndrome with short coupling interval https://www.malacards.org/card/torsade_de_pointes_short_coupled_variant https://www.malacards.org/card/torsade_de_pointes_syndrome_with_short_coupling_interval MEDGEN:462201 UMLS:C3150851 GARD:0016651 Orphanet:51084 OMIM:613600 MONDO:0013317 SCTID:718104007 Torsade-de-pointes (TdP) syndrome with short coupling interval is a very rare variant of Torsade de pointes, a polymorphic ventricular tachycardia, which is characterized by a short coupling interval of the first TdP beat on electrocardiogram in the absence of any structural heart disease. It manifests in early adulthood with syncope, often results in ventricular fibrillation and shows a high risk of sudden cardiac death.