has material basis in germline mutation in DNMT1 sleep-wake disorder hereditary sensory neuropathy-deafness-dementia syndrome https://www.malacards.org/card/hereditary_sensory_and_autonomic_neuropathy_type_1 https://www.malacards.org/card/neuropathy_hereditary_sensory_type_ie HSN1E HSAN1E DOID:0070158 hereditary sensory neuropathy with hearing loss and dementia UMLS:C3279885 GARD:0011927 neuropathy, hereditary sensory, type IE MEDGEN:481515 Orphanet:456318 Hereditary Sensory and Autonomic Neuropathy Type 1E hereditary sensory neuropathy-sensorineural hearing loss-dementia syndrome NORD:1903 HSNIE DNMT1-related dementia, deafness, and sensory neuropathy hereditary sensory and autonomic neuropathy type 1E A hereditary sensory neuropathy characterized by adult onset of progressive peripheral sensory loss, progressive hearing impairment, and early-onset dementia that has material basis in heterozygous mutation in the DNMT1 gene on chromosome 19p13. MESH:C580162 OMIM:614116 MONDO:0013584 hereditary dementia hereditary sensory and autonomic neuropathy type 1 inherited neurodegenerative disorder