has material basis in germline mutation in MSTN hereditary disease muscle tissue disorder myostatin-related muscle hypertrophy https://rarediseases.info.nih.gov/diseases/10238/myostatin-related-muscle-hypertrophy https://www.malacards.org/card/muscle_hypertrophy https://www.malacards.org/card/myostatin_related_muscle_hypertrophy muscle hypertrophy MEDGEN:418994 HGNC:4223 MONDO:0013598 DOID:0111072 ICD9:756.89 MESH:C536106 Orphanet:275534 UMLS:C2931112 SCTID:699185005 Myostatin-related muscle hypertrophy is a rare condition characterized by reduced body fat and increased muscle size. Affected individuals have up to twice the usual amount of muscle mass in their bodies. They also tend to have increased muscle strength. This condition is not known to cause any medical problems, and affected individuals are intellectually normal. Myostatin-related muscle hypertrophy is caused by mutations in the MSTN gene. It follows an incomplete autosomal dominant pattern of inheritance. OMIM:614160 MSLHP