has material basis in germline mutation in PRX Charcot-Marie-Tooth disease type 4F https://github.com/monarch-initiative/mondo/issues/4521 https://rarediseases.info.nih.gov/diseases/12441/charcot-marie-tooth-disease-type-4f https://www.malacards.org/card/charcot_marie_tooth_disease_demyelinating_type_4f https://www.malacards.org/card/charcot_marie_tooth_disease_type_4f_2 Prx Charcot-Marie-Tooth disease type 4 icd11.foundation:330503211 MEDGEN:761704 CMT4F OMIM:614895 Orphanet:99952 MONDO:0013959 Charcot-Marie-Tooth disease type 4F (CMT4F) is a severe, demyelinating subtype of Charcot-Marie-Tooth disease type 4 characterized by the childhood onset of a slowly-progressing typical CMT phenotype (i.e. distal muscle weakness and atrophy, as well as pes cavus) that presents severe sensory loss (frequently with sensory ataxia), moderately to severely reduced motor nerve conduction velocities and almost invariable absence of sensory nerve action potentials, and delayed motor milestones. Charcot-Marie-Tooth disease, demyelinating, type 4F PRX Charcot-Marie-Tooth disease type 4 GARD:0012441 UMLS:C3540453 Charcot-Marie-Tooth disease, type 4F Charcot-Marie-Tooth disease type 4 caused by mutation in PRX Charcot-Marie-Tooth disease type 4 caused by mutation in Prx SCTID:715801001 DOID:0110193 Charcot-Marie-Tooth disease type 4