has material basis in germline mutation in DGKE familial nephrotic syndrome hereditary nephritis immunoglobulin-mediated membranoproliferative glomerulonephritis https://github.com/monarch-initiative/mondo/issues/8517 https://github.com/monarch-initiative/mondo/issues/8518 https://www.malacards.org/card/nephrotic_syndrome_type_7 nephrotic syndrome, type 7 MONDO:0014005 immune complex mediated membranoproliferative glomerulonephritis UMLS:C3554330 MEDGEN:767244 NPHS7 immunoglobulin-mediated membranoproliferative glomerulonephritis immunoglobulin-mediated MPGN NANDO:1200726 Ig-mediated membranoproliferative glomerulonephritis OMIM:615008 GARD:0017506 DOID:0080388 membranoproliferative glomerulonephritis type I mesangiocapillary glomerulonephritis type 1 nephrotic syndrome, type 7, with membranoproliferative glomerulonephritis Orphanet:329903 NCIT:C123055 Ig-mediated MPGN Glomerulonephritis characterized by mesangial proliferation, endocapillary proliferation, and glomerular capillary wall remodeling with immune complex deposits from classical complement pathway activation. atypical hemolytic-uremic syndrome primary membranoproliferative glomerulonephritis