has material basis in germline mutation in disease arises from feature disease has basis in feature STEAP3 Abnormality of iron homeostasis anemia, hypochromic microcytic with iron overload congenital anemia severe congenital hypochromic anemia with ringed sideroblasts https://github.com/monarch-initiative/mondo/issues/4069 https://www.malacards.org/card/anemia_hypochromic_microcytic_with_iron_overload_2 MONDO:0014094 GARD:0017364 STEAP3/TSAP6-related sideroblastic anemia is a very rare severe non-syndromic hypochromic anemia, which is characterized by transfusion-dependent hypochromic, poorly regenerative anemia, iron overload, resembling non-syndromic sideroblastic anemia except for increased erythrocyte protoporphyrin levels. UMLS:C3808920 severe congenital hypochromic sideroblastic anemia anemia, hypochromic microcytic, with iron overload type 2 OMIM:615234 severe congenital hypochromic sideroblastic anaemia AHMIO2 MEDGEN:815250 Orphanet:300298 SCTID:725463007 anemia, hypochromic microcytic, with iron overload 2 hereditary anemia inherited sideroblastic anemia