has material basis in germline mutation in MARS1 hereditary pulmonary alveolar proteinosis severe early-onset pulmonary alveolar proteinosis due to MARS deficiency https://github.com/monarch-initiative/mondo/issues/2420 https://www.malacards.org/card/interstitial_lung_and_liver_disease GARD:0017746 MONDO:0014206 UMLS:C4225400 interstitial lung and liver disease PAP, Reunion island type hereditary pulmonary alveolar proteinosis with hepatic involvement MEDGEN:895551 Orphanet:440427 ILLD OMIM:615486 infantile liver failure syndrome 2 pulmonary alveolar proteinosis, Reunion island type