has material basis in germline mutation in IKBKB severe combined immunodeficiency due to IKK2 deficiency https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/immunodeficiency_15b immunodeficiency type 15 SCID due to IKK2 deficiency MEDGEN:1648569 UMLS:C4747743 IMD15 Orphanet:397787 GARD:0017641 OMIM:615592 MONDO:0014267 immunodeficiency 15 immunodeficiency 15B Severe combined immunodeficiency due to IKK2 deficiency is a rare, genetic form of primary immunodeficiency characterized by life-threatening bacterial, fungal and viral infections with the onset in infancy, and failure to thrive. Typically, hypogammaglobulinemia or agammaglobulinemia and normal levels of T and B cells are present. DOID:0111959 T+ B+ severe combined immunodeficiency