has material basis in germline mutation in TAF2 syndromic intellectual disability hereditary disease microcephaly-thin corpus callosum-intellectual disability syndrome https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/5588 https://www.malacards.org/card/neurodevelopmental_disorder_with_feeding_difficulties_thin_corpus_callosum_and_foot_deformity Microcephaly-thin corpus callosum-intellectual disability syndrome is a rare, genetic, syndromic intellectual disability disease characterized by progressive postnatal microcephaly and global developmental delay, as well as moderate to profound intellectual disability, difficulty or inability to walk, pyramidal signs (including spasticity, hyperreflexia and extensor plantar response) and thin corpus callosum revealed by brain imaging. Ophthalmologic signs (including nystagmus, strabismus and abnormal retinal pigmentation), foot deformity and genital anomalies may also be associated. mental retardation, autosomal recessive type 40 intellectual disability, autosomal recessive 40 Orphanet:397951 MONDO:0014273 MEDGEN:816410 mental retardation, autosomal recessive 40 intellectual disability, autosomal recessive type 40 intellectual developmental disorder, autosomal recessive 40 DOID:0081205 GARD:0017645 microcephaly-thin corpus callosum-intellectual disability syndrome MRT40 OMIM:615599 UMLS:C3810080 multiple congenital anomalies/dysmorphic syndrome-intellectual disability