has material basis in germline mutation in GLI2 autosomal dominant disease syndromic disease postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome https://github.com/monarch-initiative/mondo/issues/6751 https://www.malacards.org/card/culler_jones_syndrome https://www.malacards.org/card/postaxial_polydactyly_anterior_pituitary_anomalies_facial_dysmorphism_syndrome OMIM:615849 MEDGEN:862916 DOID:0080328 Culler-Jones syndrome GARD:0013349 Pallister-Hall syndrome 2 MONDO:0014369 UMLS:C4014479 Postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome is a rare, genetic developmental defect during embryogenesis characterized primarily by congenital hypopituitarism and/or postaxial polydactyly. It can be associated with short stature, delayed bone age, hypogonadotropic hypogonadism, and/or midline facial defects (e.g. hypotelorism, mild midface hypoplasia, flat nasal bridge, and cleft lip and/or palate). Hypoplastic anterior pituitary and ectopic posterior pituitary lobe are frequent findings on MRI examination. Orphanet:420584 CJS dysostosis non-acquired combined pituitary hormone deficiency congenital limb malformation