has material basis in germline mutation in TRPV3 obsolete nonepidermolytic palmoplantar keratoderma isolated focal non-epidermolytic palmoplantar keratoderma https://github.com/monarch-initiative/mondo/issues/6749 https://github.com/monarch-initiative/mondo/issues/6877 https://www.malacards.org/card/palmoplantar_keratoderma_nonepidermolytic_focal_2 FNEPPK2 DOID:0111708 MEDGEN:895056 MONDO:0014622 OMIM:616400 palmoplantar keratoderma, nonepidermolytic, focal 2 GARD:0017781 DOID:0111711 Orphanet:448264 palmoplantar keratoderma, nonepidermolytic, focal type 2 UMLS:C4225339 focal palmoplantar keratoderma