has material basis in germline mutation in PER3 advanced sleep phase syndrome 3 https://www.malacards.org/card/advanced_sleep_phase_syndrome_familial_3 advanced sleep phase syndrome type 3 GARD:0016165 MEDGEN:909447 PER3 advanced sleep phase syndrome advanced sleep phase syndrome, familial, type 3 advanced sleep phase syndrome caused by mutation in PER3 Any advanced sleep phase syndrome in which the cause of the disease is a mutation in the PER3 gene. advanced sleep phase syndrome, familial, 3 FASPS3 UMLS:C4225169 OMIM:616882 DOID:0110013 MONDO:0014814 advanced sleep phase syndrome