has material basis in germline mutation in MAFB Duane retraction syndrome Duane retraction syndrome 3 with or without deafness https://rarediseases.info.nih.gov/diseases/10691/duane-syndrome-type-3 https://www.malacards.org/card/duane_retraction_syndrome_3_with_or_without_deafness OMIM:617041 GARD:0010691 Duane syndrome type 3 DOID:0061029 MEDGEN:934719 MAFB Duane retraction syndrome Duane retraction syndrome caused by mutation in MAFB MONDO:0014880 Duane syndrome type 3 is a disorder of eye movement.The affected eye, or eyes, has limited ability to move both inward toward the nose and outward toward the ears. The eye opening narrows and the eyeball pulls in when looking inward toward the nose. About 15 percent of all cases of Duane syndrome are type 3. Most cases occur without other signs and symptoms.In most people with Duane syndrome type 3, the cause is unknown; but it can sometimes be caused by mutations in the CHN1 gene and inherited in an autosomal dominant fashion. Duane retraction syndrome 3 UMLS:C4310752 DURS3 Duane retraction syndrome 3 with or without deafness