disease arises from feature disease has basis in feature movement disorder neurodegenerative disease GRN-related frontotemporal lobar degeneration with Tdp43 inclusions progressive non-fluent aphasia https://rarediseases.info.nih.gov/diseases/10793/progressive-non-fluent-aphasia https://www.malacards.org/card/progressive_non_fluent_aphasia Progressive non-fluent aphasia (PNFA) is a form of frontotemporal dementia (FTD), characterized by agrammatism, laborious speech, alexia, and agraphia, frequently accompanied by apraxia of speech (AOS). Language comprehension is relatively preserved. Orphanet:100070 SCTID:716281000 non-fluent variant PPA non-fluent primary progressive aphasia Primary Progressive Nonfluent aphasia MEDGEN:148373 UMLS:C0751706 MedDRA:10029542 MESH:D057178 DOID:0081390 MONDO:0015059 GARD:0010793 NCIT:C85025 Agramatic variant of PPA Agramatic variant of primary progressive aphasia