disease has major feature autosomal dominant disease dementia early-onset autosomal dominant Alzheimer disease https://www.malacards.org/card/early_onset_autosomal_dominant_alzheimer_disease Orphanet:1020 MONDO:0015140 early-onset, autosomal dominant Alzheimer disease EOFAD A progressive dementia with reduction of cognitive functions. It presents the same phenotype as sporadic Alzheimer disease (AD) but has an early age of onset, usually before 60 years old. early-onset familial autosomal dominant Alzheimer disease GARD:0012798 familial Alzheimer disease