anemia idiopathic aplastic anemia sideroblastic anemia https://www.malacards.org/card/sideroblastic_anemia anaemia sideroblastic MONDO:0015194 SCTID:41841004 NCIT:C36078 DOID:8955 MedDRA:10040661 NANDO:2100179 sideroblastic anemia ICD9:285.0 UMLS:C0002896 MESH:D000756 NANDO:2200616 MEDGEN:8067 anemia sideroblastic A group of rare heterogeneous inherited or acquired bone marrow disorders, isolated or part of a syndrome, characterized by decreased hemoglobin synthesis, because of defective use of iron (although plasmatic iron levels may be normal or elevated) and the presence of ringed sideroblasts in the bone marrow due to the pathologic iron overload in mitochondria as visualized by Perls' staining. The group encompasses (idiopathic) acquired sideroblastic anemia and constitutional sideroblastic anemias. The latter include syndromic sideroblastic anemias such as Pearson syndrome, mitochondrial mypathy and sideroblastic anemias, x-linked sideroblastic anemia-ataxia, thiamine responsive megaloblastic anemia syndrome and nonsyndromic sideroblastic anemias comprising x-linked and autosomal recessive sideroblastic anemias. Orphanet:1047 GARD:0018714