disease has location disease arises from structure disease arises from alteration in structure parafollicular cell neuroendocrine carcinoma carcinoma thyroid gland follicular carcinoma medullary thyroid gland carcinoma https://www.malacards.org/card/medullary_thyroid_carcinoma GARD:0007004 NCIT:C3879 SCTID:255032005 thyroid medullary carcinoma medullary carcinoma of thyroid parafollicular cell carcinoma medullary carcinoma of the thyroid gland MedDRA:10027101 thyroid carcinoma, medullary icd11.foundation:578519098 carcinoma, C-cell, malignant A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy. MEDGEN:66772 thyroid cancer, medullary DOID:3973 medullary thyroid cancer medullary carcinoma medullary thyroid cancer (MTC) MTC UMLS:C0238462 thyroid gland medullary cancer C cell carcinoma Orphanet:1332 thyroid gland neuroendocrine carcinoma thyroid gland medullary carcinoma medullary carcinoma of the thyroid medullary thyroid gland carcinoma NANDO:2201054 medullary thyroid carcinoma medullary carcinoma of thyroid gland HP:0002865 MONDO:0015277 ONCOTREE:THME THME carcinoma of parafollicular cell