leukoencephalopathy with bilateral anterior temporal lobe cysts https://www.malacards.org/card/leukoencephalopathy_with_bilateral_anterior_temporal_lobe_cysts icd11.foundation:138159250 MONDO:0015348 Orphanet:139444 GARD:0019917 MEDGEN:930413 Leukoencephalopathy with bilateral anterior temporal lobe cysts is a nonprogressive neurological disorder marked by intellectual deficit, spasticity and motor retardation associated with characteristic MRI findings of anterior bilateral temporal lobe cysts and multilobar leukoencephalopathy. So far, around 30 cases have been reported in the literature. Onset occurs in the first few months of life. Sensorineural deafness and microcephaly have also been reported. The etiology is unknown but an autosomal recessive mode of inheritance has been suggested. UMLS:C4304744 leukodystrophy