disease arises from structure disease arises from alteration in structure chromosome 1 (Human) ring chromosome 1 https://www.malacards.org/card/ring_chromosome_1 MESH:C535361 Orphanet:1437 UMLS:C0265395 R1 GTR:AN0102272 GARD:0001320 Ring 1 Ring chromosome type 1 Ring chromosome 1 syndrome is an autosomal anomaly characterized by variable clinical features, most commonly including significant intrauterine and postnatal growth failure, developmental delay, intellectual disability, microcephaly, and dysmorphic facial features. Some less frequent clinical features are dysgenesis of corpus callosum, atrial septal defect, rocker bottom feet and clinodactyly. NCIT:C36474 MEDGEN:539215 r(1) syndrome Ring chromosome 1 syndrome chromosome 1 ring SCTID:47017007 chromosome 1, ring MONDO:0015430 chromosome 1 disorder ring chromosome disorder