disease arises from structure disease arises from alteration in structure chromosome 10 (Human) syndromic intellectual disability syndromic disease ring chromosome 10 https://github.com/monarch-initiative/mondo/issues/5588 https://rarediseases.info.nih.gov/diseases/1322/ring-chromosome-10 https://www.malacards.org/card/ring_chromosome_10 Ring chromosome 10 syndrome MESH:C538086 Ring chromosome 10 syndrome is characterized by intellectual deficit, growth retardation, and various dysmorphic features. Less than 20 cases have been described. The main features are low birth weight, microcephaly, stubby nose with a prominent nasal bridge, hypertelorism, strabismus, wide-set nipples, single transverse palmar creases, and clinodactyly. Boys have undescended testes and hypoplastic scrotum. Congenital heart disease, hydronephrosis or renal hypoplasia was present in some of the cases. Ring chromosome type 10 MONDO:0015431 Orphanet:1438 Ring 10 GARD:0001322 UMLS:C0265438 SCTID:86997002 MEDGEN:539252 r10 chromosome 10 ring chromosome 10 disorder ring chromosome disorder