disease arises from structure disease arises from alteration in structure chromosome 4 (Human) ring chromosome 4 https://rarediseases.info.nih.gov/diseases/1339/ring-chromosome-4 https://www.malacards.org/card/ring_chromosome_4 chromosome 4 ring NORD:1671 Orphanet:1447 Ring chromosome type 4 Ring chromosome 4 syndrome is an autosomal anomaly characterized by variable clinical features, most commonly including significant intrauterine and postnatal growth retardation, developmental delay, intellectual disability, microcephaly, and dysmorphic facial features. Some less frequent features are cleft lip and/or cleft palate, congenital cardiovascular, gastrointestinal and genitourinary system anomalies. r(4) syndrome MEDGEN:75571 R4 GARD:0001339 rose cluster 4 syndrome r(4) Ring 4 MONDO:0015439 SCTID:81678004 NCIT:C121983 MESH:C537636 UMLS:C0265407 Ring chromosome 4 syndrome chromosome 4 disorder ring chromosome disorder