disease has basis in disruption of disease caused by disruption of macrophage activation secondary hemophagocytic lymphohistiocytosis macrophage activation syndrome https://github.com/monarch-initiative/mondo/issues/9285 https://rarediseases.info.nih.gov/diseases/12124/macrophage-activation-syndrome https://www.malacards.org/card/macrophage_activation_syndrome MEDGEN:242753 EFO:1001806 UMLS:C1096155 reactive hemophagocytic lymphohistiocytosis GARD:0012124 NCIT:C114471 A complication of rheumatic disease that is caused by excessive activation and uncontrolled proliferation of T lymphocytes and well-differentiated macrophages. It is characterized by fever, pancytopenia, liver insufficiency, coagulopathy and neurologic symptoms. Orphanet:158061 MONDO:0015545 MedDRA:10053867 MESH:D055501 SCTID:430478003 MAS