limbic encephalitis https://rarediseases.info.nih.gov/diseases/8742/limbic-encephalitis https://www.malacards.org/card/limbic_encephalitis MONDO:0015588 MESH:D020363 A group of autoimmune conditions characterized by inflammation of the limbic system and other parts of the brain.The cardinal sign of limbic encephalitis is a severe impairment of short-term memory; however,symptoms may also include confusion, psychiatric symptoms, and seizures.The symptomstypically develop over a few weeks or months, but they may evolve over a few days. Limbic encephalitis is often associated with an underlying neoplasm (paraneoplastic limbic encephalitis); however some cases never have a neoplasm identified (non-paraneoplastic limbic encephalitis). Delayed diagnosis is common, but improvements are being made to assist in early detection. Various tests including imaging studies (MRI, PET) laboratory tests (CSF analysis), and tests that measure the electrical activity of the brain (EEG) may be utilized to confirm a diagnosis. Treatment includes removal of the neoplasm (if identified) and immunotherapy. GARD:0008742 SCTID:230192003 MEDGEN:137895 UMLS:C0338430 Orphanet:163892 DOID:0080741 ICD9:323.9 encephalitis