limbic encephalitis non-herpetic acute limbic encephalitis Non-herpetic acute limbic encephalitis is a rare neuroinflammatory/neuroautoimmune disease characterized by an acute (or subacute) onset of disturbance of consciousness (occasionally presenting as convulsions) and high fever, associated with cerebral lesions (on magnetic resonance imaging) that are restricted to the limbic system (particularly the hippocampi and amygdalae), in the absence of viral, bacterial, fungal, paraneoplastic and other disorders. SCTID:764998005 GARD:0025067 Orphanet:163924 MEDGEN:1646654 MONDO:0015596 UMLS:C4707262