has material basis in germline mutation in POLA1 X-linked intellectual disability, van Esch type https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/5588 https://www.malacards.org/card/van_esch_odriscoll_syndrome DOID:0111840 MONDO:0015601 MEDGEN:930741 X-linked intellectual deficit, Van Esch type is characterized by mild to moderate intellectual deficit associated with low birth weight, short stature, microcephaly and variable hypergonadotropic hypogonadism. GARD:0017008 OMIM:301030 Van Esch-O'Driscoll syndrome, X-linked recessive UMLS:C4305072 mental retardation, X-Linked, syndromic, Van Esch-O'Driscoll type Van Esch-O'Driscoll syndrome VEODS SCTID:718914002 Orphanet:163976 X-linked syndromic intellectual disability