has characteristic has characteristic scleromyxedema https://rarediseases.info.nih.gov/diseases/7615/scleromyxedema https://www.malacards.org/card/scleromyxedema generalized lichenoid papular eruption MESH:D053718 generalised papular and sclerodermoid Scleromyxedema is a rare, severe skin disorder. Signs and symptoms include abnormal accumulation of mucin in the skin (mucinosis), causing papular and sclerodermoid bumps; increased production of fibroblasts (connective tissue cells) in the absence of a thyroid disorder; and monoclonal gammopathy (abnormal proteins in the blood). It often involves internal organs and may affect various body systems. The cause of scleromyxedema is not known. There is no standard treatment. Management may involve the use of intravenous immunoglobulin (IVIG), plasmapheresis, thalidomide and corticoids, or more aggressive interventions, such as autologous bone marrow transplantation. MEDGEN:120476 mucinosis, papular NCIT:C85061 generalized papular and sclerodermoid generalised lichenoid papular eruption lichen myxedematosus SCTID:402468007 myxedematosus, lichen papular mucinosis GARD:0007615 UMLS:C0263390 Scleromyxedema generalized papular and sclerodermoid lichen myxedematosus generalised papular and sclerodermoid lichen myxedematosus scleromyxoedema ICD9:701.8 MedDRA:10055046 MONDO:0015665 Arndt-Gottron disease Orphanet:167635 lichen myxedematosus distributed