myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2 myeloid neoplasm associated with PDGFRB rearrangement https://github.com/monarch-initiative/mondo/issues/3845 https://www.malacards.org/card/myeloid_and_lymphoid_neoplasms_associated_with_pdgfrb_rearrangement MONDO:0015690 myeloid neoplasms with PDGFRB rearrangement SCTID:724642009 myeloid neoplasms associated with PDGFRB rearrangement A rare, malignant, neoplastic disease characterized by clonal proliferation of myeloid and/or lymphoid precursors harboring rearrangements in the PDGFRB gene, in the blood, bone marrow and often other tissues as well (spleen, lymph nodes, skin, etc.). It usually presents as chronic myelomonocytic leukemia with eosinophilia, chronic eosinophilic leukemia, atypical chronic myelogenous leukemia, juvenile myelomonocytic leukemia, myelodysplastic syndrome, acute myeloid leukemia or acute lymphoblastic leukemia. Patients usually present with anemia, leukocytosis, monocytosis, eosinophilia and/or splenomegaly, or systemic symptoms, such as fever, sweating and/or weight loss. icd11.foundation:625932159 ONCOTREE:MLNPDGFRB DOID:0080166 myeloid and lymphoid neoplasms with PDGFRB rearrangement MEDGEN:758646 ICDO:9966/3 Orphanet:168950 NCIT:C84276 GARD:0020107 myeloid/lymphoid neoplasms with PDGFRB rearrangement UMLS:C3472621