hereditary disease dysmorphism-cleft palate-loose skin syndrome https://www.malacards.org/card/dysmorphism_cleft_palate_loose_skin_syndrome UMLS:C4706366 MEDGEN:1642311 Orphanet:1779 Dysmorphism-cleft palate-loose skin syndrome is a rare, genetic developmental defect during embryogenesis characterized by severe psychomotor delay, intellectual disability, congential, symmetrical circumferential skin creases of arms and legs, cleft palate, and facial dysmorphism (incl. elongated face, high forehead, blepharophimosis, short palpebral fissures, microphthalmia, microcornea, epicanthic folds, telecanthus, microtia, posteriorly angulated ears, broad nasal bridge, microstomia and micrognathia). Additional features reported include short stature, microcephaly, hypotonia, pectus excavatum, severe scoliosis, hypoplastic scrotum, and mixed hearing loss. GARD:0002009 MONDO:0015782