primary cutaneous T-cell lymphoma primary cutaneous gamma/delta-positive T-cell lymphoma https://github.com/monarch-initiative/mondo/issues/6739 https://github.com/monarch-initiative/mondo/issues/6746 https://github.com/monarch-initiative/mondo/issues/6749 https://github.com/monarch-initiative/mondo/issues/8583 https://www.malacards.org/card/primary_cutaneous_gamma_delta_positive_t_cell_lymphoma Reason of obsoletion: duplicate. This will be merged with MONDO:0850459 primary cutaneous gamma-delta t-cell lymphoma Orphanet:178533 GARD:0020158 Primary cutaneous gamma/delta-positive T-cell lymphoma is a rare, usually aggressive, subtype of cutaneous T-cell lymphoma characterized by infiltration of the epidermis, dermis or subcutaneous tissue by a clonal population of mature, gamma/delta positive cytotoxic T-cells. Typically it presents with ulcerating plaques, tumors, or subcutaneous nodules on the skin of the extremities, however, frequent involvement of mucosal and extranodal sites (such as the nasal cavity, gastrointestinal tract or lungs) is also observed. Cases associated with panniculitis may present with hemophagocytic syndrome (abrupt onset of fever, rash, cytopenia, hepatosplenomegaly and neurological compromise). Infiltration of lymph nodes, spleen and bone marrow is uncommon and resistance to multilineage chemotherapy is reported. 2025-04-01 MONDO:0015812