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    <!-- http://purl.obolibrary.org/obo/MONDO_0002648 -->

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    <!-- http://purl.obolibrary.org/obo/MONDO_0003950 -->

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    <!-- http://purl.obolibrary.org/obo/MONDO_0015873 -->

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        <ns4:IAO_0000115>Paget disease of the nipple describes a rare presentation of breast cancer, seen most frequently in women aged 50-60, manifesting with nipple drainage and itching, erythema, crusty and excoriated nipple, thickened plaques, and hyperpigmentation (less frequently). It is due to tumor cells invading the nipple-areola complex and represents 1-3% of all new breast cancer diagnoses.</ns4:IAO_0000115>
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