anemia aplastic anemia https://www.malacards.org/card/rare_aplastic_anemia About 75% of aplastic anemia cases are classified as idiopathic. In about 15% of cases a drug or infection can be identified that precipitates the aplasia, although why only some individuals are susceptible is unclear. In about 5 to 10% of patients, the aplastic anemia is constitutional (ie familial or inherited, or presents with one or more associated somatic abnormalities) [OMIM:609135] NANDO:2100201 Orphanet:182040 NANDO:1200295 NANDO:2200693 NCIT:C2870 MONDO:0015909 GARD:0020234 DOID:12449 OMIM:609135 NANDO:1200301 MEDGEN:8063 ICD9:284.8 Anemia resulting from bone marrow failure (aplastic or hypoplastic bone marrow). The production of erythroblasts and red cells is markedly decreased, and it may be associated with decreased production of granulocytes (granulocytopenia) and platelets (thrombocytopenia) as well. Aplastic anemia may be idiopathic or secondary due to bone marrow damage by toxins, radiation, or immunologic factors. UMLS:C0002874 MESH:D000741 SCTID:306058006 ICD9:284.9 telomere syndrome